Rickettsial TAIL COMB zoonotic diseases, in particular scrub typhus, murine typhus, and tick typhus, are caused by Orientia tsutsugamushi, Rickettsia typhi, and Rickettsia honei infections.Rickettsiae exposure is typically related to a rodent host in various habitats of marginal regions, including between rural areas and communities such as the Sal
The coronavirus 2019 (COVID-19) pandemic has disproportionately impacted lesbian, gay, bisexual, transgender, queer (LGBTQ+) people.Despite developing safe and effective COVID-19 vaccines, LGBTQ+ communities still faces challenges due to inequitable access and vaccine hesitancy.Vaccine hesitancy is a delay in the acceptance or refusal of vaccines d
Abstract Background The PI3K/AKT pathway is activated through PIK3CA or AKT1 mutations and PTEN loss in breast cancer.We conducted a phase II trial with an allosteric AKT inhibitor MK-2206 in patients with advanced breast cancer who had tumors with PIK3CA/AKT1 mutations and/or PTEN loss/mutation.Methods The primary endpoint was objective response r
The self-assessment basedon Annex A of the ISO 9004:2009 standard is a very Jewelry Armoires practical diagnostic tool and also very powerful for capturing the image of the organization quickly.It enables to have answers to questions suchas: what are the strengths and weakness of our organization? Do we have adequate processes, resources and compet